Cosmosil COSMOSIL C22-AR-II, C8-MS, C4-MS, TMS-MS, PE-MS COSMOSIL C22-AR-II, C8-MS, C4-MS, TMS-MS, PE-MS.. Product #: VEL00492

COSMOSIL C22-AR-II, C8-MS, C4-MS, TMS-MS, PE-MS

COSMOSIL C22-AR-II, C8-MS, C4-MS, TMS-MS, PE-MS

Brand: Cosmosil
Product Code: VEL00492

COSMOSIL C22-AR-II, C8-MS, C4-MS, TMS-MS, PE-MS

COSMOSIL alkyl type columns also include stationary phases with packing materials of C22 (Dococyl group), C8 (Octadecyl group), C4(Butyl group) and TMS (Trimethyl group). The order of retention force by hydrophobicity of each packing material is C22=C18>C8>C4>TMS. The columns having lower hydrophobicity than C18 or C22 are effective for separation of high hydrophobic compounds and compounds with big difference in hydrophobic. Hydrophobicity of C22 is about the same as C18. However, stere-oselectivity of C22 is higher than C18, and so C22 may provide better separation.

 

COSMOSIL Alkyl Type HPLC Columns
  C22-AR-II C8-MS C4-MS TMS-MS 
 Structure  COSMOSIL C22-AR-II Structure  COSMOSIL C8-MS Structure  COSMOSIL C4-MS Structure  COSMOSIL TMS-MS Structure
 Base Material Spherical Silica Gel
 Particle Sizes Available 5um
 Pore Size  120A
 Surface Area  300m2/g
 pH Range  2.0 - 8.0
 USP Code -  L7 L26 L13
 Carbon Load  19% 10% 7% 5% 

 

Effect of Alkyl Chain Length on Reversed Phase

The shorter alkyl chain stationary phase shows shorter retention time for non-polar compounds such as benzene and toluene and longer retention for polar compounds such as acetophenone and benzoate.

COSMOSIL Alkyl Columns 1 

Condition
Column Size 4.6 mm I.D. x 150 mm Sample1. Acetophenone 0.05 µg
Mobile Phase Methanol : Water = 60 : 40 2. Methyl Benzoate 0.5 µg
Flow Rate 1.0 ml/min 3. Benzene 2.0 µg
Temperature 30°C 4. Toluene 2.0 µg
Detection UV 254 nm    

 

Ordering Information

 

Particle Size Description Column Dimensions Part Number
5um COSMOSIL 5C22-AR-II Column 4.6mmI.D. x 50mm 05848-41
5um COSMOSIL 5C22-AR-II Column 4.6mmI.D. x 100mm 05849-31
5um COSMOSIL 5C22-AR-II Column 4.6mmI.D. x 150mm 04598-51
5um COSMOSIL 5C22-AR-II Column 4.6mmI.D. x 250mm 04599-41
5um COSMOSIL 5C22-AR-II Column 6.0mmI.D. x 150mm 05850-91
5um COSMOSIL 5C22-AR-II Column 6.0mmI.D. x 250mm 05851-81
5um COSMOSIL 5C22-AR-II Column 10.0mmI.D. x 250mm 04969-91
5um COSMOSIL 5C22-AR-II Column 20.0mmI.D. x 250mm 05183-41
       
5um COSMOSIL 5C8-MS Packed Column 4.6mmI.D. x 50mm 38153-11
5um COSMOSIL 5C8-MS Packed Column 4.6mmI.D. x 100mm 38154-01
5um COSMOSIL 5C8-MS Packed Column 4.6mmI.D. x 150mm 38155-91
5um COSMOSIL 5C8-MS Packed Column 4.6mmI.D. x 250mm 38156-81
5um COSMOSIL 5C8-MS Packed Column 6.0mmI.D. x 150mm 38157-71
5um COSMOSIL 5C8-MS Packed Column 6.0mmI.D. x 250mm 38158-61
5um COSMOSIL 5C8-MS Packed Column 10.0mmI.D. x 250mm 38159-51
5um COSMOSIL 5C8-MS Packed Column 20.0mmI.D. x 250mm 38160-11
       
5um COSMOSIL 5C4-MS Packed Column 4.6mmI.D. x 50mm 38163-81
5um COSMOSIL 5C4-MS Packed Column 4.6mmI.D. x 100mm 38164-71
5um COSMOSIL 5C4-MS Packed Column 4.6mmI.D. x 150mm 38165-61
5um COSMOSIL 5C4-MS Packed Column 4.6mmI.D. x 250mm 38166-51
5um COSMOSIL 5C4-MS Packed Column 6.0mmI.D. x 150mm 38167-41
5um COSMOSIL 5C4-MS Packed Column 6.0mmI.D. x 250mm 38168-31
5um COSMOSIL 5C4-MS Packed Column 10.0mmI.D. x 250mm 38169-21
5um COSMOSIL 5C4-MS Packed Column 20.0mmI.D. x 250mm 38170-81
       
5um COSMOSIL 5TMS-MS Packed Column 4.6mmI.D. x 50mm 38173-51
5um COSMOSIL 5TMS-MS Packed Column 4.6mmI.D. x 100mm 38174-41
5um COSMOSIL 5TMS-MS Packed Column 4.6mmI.D. x 150mm 38175-31
5um COSMOSIL 5TMS-MS Packed Column 4.6mmI.D. x 250mm 38176-21
5um