Cosmosil COSMOSIL C18-AR-II COSMOSIL C18-AR-II HPLC Columns.. Product #: VEL00487

COSMOSIL C18-AR-II

COSMOSIL C18-AR-II

Brand: Cosmosil
Product Code: VEL00487

COSMOSIL C18-AR-II HPLC Columns

COSMOSIL C18-AR-II structureThe COSMOSIL C18-AR-II packed column features a polymeric   type of C18 reversed phase material. The column employs an ultra-pure silica gel low in metal impurities and has near-perfect end-capping. In addition, it has stronger acid resistance than the old COSMOSIL C18-AR. The COMSOSIL C18-AR-II column is especially effective for the separation of chelating compounds as well as both acidic and basic compounds.

 Main Characteristics

  • Excellent stability and long lifetime at low pH
  • Recommended when using acidic mobile phase conditions
  • Polymeric bonding offers superior molecular shape selectivity

 

COSMOSIL C18-AR-II
 Base Material Silica Gel
 Particle Sizes Available 3, 5, 15um
 Pore Size 120Å
 Surface Area 330m2/g
 pH Range 1.5 - 7.5
 USP Code L1
 Carbon Load 17%

 

COSMOSIL C18-AR-II 1Acidic Resistance

The acidic resistance of COSMOSIL 5C18-AR-II is much improved compared with commercially available monomeric type octadecyl stationary phases. It retains high performance even in case of acidic mobile phases commonly used to separate acidic compounds and peptides.

Figure. Decomposition test in 0.1% Trifluoroacetic Acid solution at 60°C . Capacity factor (k') = Naphthalene, Mobile phase: 70% methanol

Applications

Organic Acid

 COSMOSIL C18-AR-II 2

Condition
Column Size 4.6 mm I.D. x 150 mm
Mobile Phase Methanol : 20 mmol/l                       Phosphoric Acid = 20 : 80
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 254 nm 0.5 AUFS
Sample
  1. Gallic Acid 0.63 µg
  2. Protocatechuic Acid 0.63 µg
  3. Gentisic Acid 0.63 µg
  4. Phthalic Acid 0.63 µg
Paraben

 COSMOSIL C18-AR-II 3

Condition
Column Size 4.6 mm I.D. x 150 mm
Mobile Phase Acetonitrile : Water = 50 : 50
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 254 nm
Sample
  1. Methyl p -Hydroxybenzoate 0.25 µg
  2. Ethyl p -Hydroxybenzoate 0.025 µg
  3. N-n -Propyl p -Hydroxybenzoate 0.025 µg
  4. n -Butyl p -Hydroxybenzoate 0.025 µg
Salicylic Acid

 COSMOSIL C18-AR-II 4

Condition
Column Size 4.6 mm I.D. x 150 mm
Mobile Phase Acetonitrile : Water = 70 : 30
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 254 nm 0.2 AUFS
Sample
  1. Methyl Salicylate 2.3 µg
  2. Ethyl Salicylate 2.6 µg
  3. Propyl Salicylate 2.3 µg
  4. Propyl Salicylate 2.3 µg
  5. Butyl Salicylate 2.6 µg
Hinokitiol

 COSMOSIL C18-AR-II 5

Condition
Column Size 4.6 mm I.D. x 150 mm
Mobile Phase Methanol : 1 mmol/l EDTA 20 mmol/l       Phosphoric Acid = 70 : 30
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 254 nm 0.5 AUFS
Sample Hinokitiol 1 µg
Acetylacetone

COSMOSIL C18-AR-II 7

 

Condition
Column Size 4.6 mm I.D. x 150 mm
Mobile Phase Acetonitrile : 20 mmol/l                       Phosphate Buffer (pH7) = 60 : 40
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 240 nm 0.2 AUFS
Sample
  1. Acetylacetone 0.76 µg
  2. 8-Quinolinol 0.70 µg
  3. Benzene 14.65 µg

 

Ordering Information

 

Particle Size Description Column Dimensions Part Number
3um COSMOSIL C18-AR-II   Column 2.0 x 50mm 05478-91
3um COSMOSIL C18-AR-II Column 4.6 x 10mm 38068-41
3um COSMOSIL C18-AR-II Column 4.6 x 50mm 38069-31
3um COSMOSIL C18-AR-II Column 4.6 x 100mm 38070-91
       
5um COSMOSIL C18-AR-II   Column 1.0 x 50mm 02955-21
5um COSMOSIL C18-AR-II Column 1.0 x 150mm 02951-61
5um COSMOSIL C18-AR-II Column 2.0 x 30mm 05098-71
5um COSMOSIL C18-AR-II Column 2.0 x 50mm 34400-81
5um COSMOSIL C18-AR-II Column 2.0 x 100mm 34469-11
5um COSMOSIL C18-AR-II Column 2.0 x 150mm 37992-51
5um COSMOSIL C18-AR-II Column 2.0 x 250mm 05272-71
5um COSMOSIL C18-AR-II Column 3.0 x 100mm 05791-71
5um COSMOSIL C18-AR-II Column 3.0 x 150mm 38028-61
5um COSMOSIL C18-AR-II Column 3.0 x 250mm 38029-51
5um COSMOSIL C18-AR-II Column 4.6 x 30mm 05877-61
5um COSMOSIL C18-AR-II Column 4.6 x 50mm 38142-51
5um COSMOSIL C18-AR-II Column 4.6 x 100mm 38143-41
5um COSMOSIL C18-AR-II Column 4.6 x 150mm 38144-31
5um C18-AR-II Column 3Lot Set 4.6 x 150mm 09396-83
5um COSMOSIL C18-AR-II Column 4.6 x 250mm 38145-21
5um COSMOSIL C18-AR-II Column 6.0 x 150mm 38146-11
5um COSMOSIL C18-AR-II Column 6.0 x 250mm