COSMOSIL C18-AR-II
COSMOSIL C18-AR-II
COSMOSIL C18-AR-II HPLC Columns
The COSMOSIL C18-AR-II packed column features a polymeric type of C18 reversed phase material. The column employs an ultra-pure silica gel low in metal impurities and has near-perfect end-capping. In addition, it has stronger acid resistance than the old COSMOSIL C18-AR. The COMSOSIL C18-AR-II column is especially effective for the separation of chelating compounds as well as both acidic and basic compounds.
Main Characteristics
- Excellent stability and long lifetime at low pH
- Recommended when using acidic mobile phase conditions
- Polymeric bonding offers superior molecular shape selectivity
| COSMOSIL C18-AR-II | |
| Base Material | Silica Gel |
| Particle Sizes Available | 3, 5, 15um |
| Pore Size | 120Å |
| Surface Area | 330m2/g |
| pH Range | 1.5 - 7.5 |
| USP Code | L1 |
| Carbon Load | 17% |
Acidic Resistance
The acidic resistance of COSMOSIL 5C18-AR-II is much improved compared with commercially available monomeric type octadecyl stationary phases. It retains high performance even in case of acidic mobile phases commonly used to separate acidic compounds and peptides.
Figure. Decomposition test in 0.1% Trifluoroacetic Acid solution at 60°C . Capacity factor (k') = Naphthalene, Mobile phase: 70% methanol
Applications
Organic Acid
| Condition | |
|---|---|
| Column Size | 4.6 mm I.D. x 150 mm |
| Mobile Phase | Methanol : 20 mmol/l Phosphoric Acid = 20 : 80 |
| Flow Rate | 1.0 ml/min |
| Temperature | 30°C |
| Detection | UV 254 nm 0.5 AUFS |
| Sample |
|
Paraben
| Condition | |
|---|---|
| Column Size | 4.6 mm I.D. x 150 mm |
| Mobile Phase | Acetonitrile : Water = 50 : 50 |
| Flow Rate | 1.0 ml/min |
| Temperature | 30°C |
| Detection | UV 254 nm |
| Sample |
|
Salicylic Acid
| Condition | |
|---|---|
| Column Size | 4.6 mm I.D. x 150 mm |
| Mobile Phase | Acetonitrile : Water = 70 : 30 |
| Flow Rate | 1.0 ml/min |
| Temperature | 30°C |
| Detection | UV 254 nm 0.2 AUFS |
| Sample |
|
Hinokitiol
| Condition | |
|---|---|
| Column Size | 4.6 mm I.D. x 150 mm |
| Mobile Phase | Methanol : 1 mmol/l EDTA 20 mmol/l Phosphoric Acid = 70 : 30 |
| Flow Rate | 1.0 ml/min |
| Temperature | 30°C |
| Detection | UV 254 nm 0.5 AUFS |
| Sample | Hinokitiol 1 µg |
Acetylacetone
| Condition | |
|---|---|
| Column Size | 4.6 mm I.D. x 150 mm |
| Mobile Phase | Acetonitrile : 20 mmol/l Phosphate Buffer (pH7) = 60 : 40 |
| Flow Rate | 1.0 ml/min |
| Temperature | 30°C |
| Detection | UV 2４0 nm 0.2 AUFS |
| Sample |
|
Ordering Information
| Particle Size | Description | Column Dimensions | Part Number |
| 3um | COSMOSIL C18-AR-II Column | 2.0 x 50mm | 05478-91 |
| 3um | COSMOSIL C18-AR-II Column | 4.6 x 10mm | 38068-41 |
| 3um | COSMOSIL C18-AR-II Column | 4.6 x 50mm | 38069-31 |
| 3um | COSMOSIL C18-AR-II Column | 4.6 x 100mm | 38070-91 |
| 5um | COSMOSIL C18-AR-II Column | 1.0 x 50mm | 02955-21 |
| 5um | COSMOSIL C18-AR-II Column | 1.0 x 150mm | 02951-61 |
| 5um | COSMOSIL C18-AR-II Column | 2.0 x 30mm | 05098-71 |
| 5um | COSMOSIL C18-AR-II Column | 2.0 x 50mm | 34400-81 |
| 5um | COSMOSIL C18-AR-II Column | 2.0 x 100mm | 34469-11 |
| 5um | COSMOSIL C18-AR-II Column | 2.0 x 150mm | 37992-51 |
| 5um | COSMOSIL C18-AR-II Column | 2.0 x 250mm | 05272-71 |
| 5um | COSMOSIL C18-AR-II Column | 3.0 x 100mm | 05791-71 |
| 5um | COSMOSIL C18-AR-II Column | 3.0 x 150mm | 38028-61 |
| 5um | COSMOSIL C18-AR-II Column | 3.0 x 250mm | 38029-51 |
| 5um | COSMOSIL C18-AR-II Column | 4.6 x 30mm | 05877-61 |
| 5um | COSMOSIL C18-AR-II Column | 4.6 x 50mm | 38142-51 |
| 5um | COSMOSIL C18-AR-II Column | 4.6 x 100mm | 38143-41 |
| 5um | COSMOSIL C18-AR-II Column | 4.6 x 150mm | 38144-31 |
| 5um | C18-AR-II Column 3Lot Set | 4.6 x 150mm | 09396-83 |
| 5um | COSMOSIL C18-AR-II Column | 4.6 x 250mm | 38145-21 |
| 5um | COSMOSIL C18-AR-II Column | 6.0 x 150mm | 38146-11 |
| 5um | COSMOSIL C18-AR-II Column | 6.0 x 250mm |